Cardinals Game Sunday: Cardinals vs. 49ers odds and prediction for Week 9 NFL game

(Photo by Kyle Terada-USA TODAY Sports) Chandler Jones
(Photo by Kyle Terada-USA TODAY Sports) Chandler Jones /

Following their first loss of the season, the Arizona Cardinals will attempt to get back in the win column in a Week 9 showdown with the San Francisco 49ers.

They almost pulled it off in the end, but unfortunately, the Arizona Cardinals walked off the field in Week 8 with their first loss of the season after falling to the Green Bay Packers in a Thursday night thriller.

After a few extra days off, the Cardinals will head out on the road to the take on the San Francisco 49ers for the second and final time this year in a matchup that figures to be a close battle between two division rivals.

Arizona Cardinals vs. San Francisco 49ers odds Week 9

Point Spread:

  • Cardinals -1.0 (-110)
  • 49ers +1.0 (-110)


  • Cardinals -120
  • 49ers +100


  • 45.0 points
    • Over  -110
    • Under -110

(Odds via WynnBet)

Arizona Cardinals vs. San Francisco 49ers prediction Week 9

There’s a gigantic factor heading into this NFC West contest and that is the status of Arizona quarterback Kyler Murray.

Murray is currently dealing with an ankle injury that he suffered against the Packers and the chances of him suiting up to face the 49ers this week are unknown.

If Murray is held out of action this weekend, Arizona will turn to their veteran backup signal-caller, Colt McCoy, to help lead them to a victory.

If Murray plays, a Cardinals win seems likely. But if he sits out and McCoy has to start, Arizona’s chances of getting a victory certainly go down.

However, San Francisco hasn’t been playing too well this season, and the Cardinals should still have enough firepower to leave the field with a win on Sunday.

Prediction: Cardinals win

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