5. At Indianapolis
Bruce Arians will be returning to Indianapolis for the first time since he was the interim head coach for the Colts and won coach of the year in 2012
This game will be something to look forward too, especially if its near the end of the season with playoff implications. Indianapolis holds a special place in Arians heart. In 2012, he was named the interim head coach after Chuck Pagano was diagnosed with Cancer. He led the Colts to a 9-3 record and was named the 2012 NFL coach of the year.
This game will feature a lot of emotion, and Arians will definitely want to win this one badly. The last time the Cardinals played the Colts was in Arizona in 2013. The Cardinals won in a blowout 40-11. Arizona last traveled to Indianapolis in 2006 when the Colts still played in the RCA Dome. They lost that one 17-13.
Expect this game, no matter when its played, to be a good one. If this game is played with playoff implications it would be one to remember.
Prediction: 24-17 Cardinals