Arizona Cardinals meet 49ers for second time

This is the second time in 3 games the Arizona Cardinals meet the San Francisco 49ers

The first game between the Arizona Cardinals and San Francisco 49ers two weeks ago on Halloween turned out to be much closer than many expected.  Could the Cardinals pull off an upset at Levi’s Stadium on Sunday?

Don’t count on it, however you never know.  The Cardinals came up just short 28-25 at State Farm Stadium on October 31st.

It could be viewed as advantage for both teams on Sunday facing each other both times within such a short amount of time.  Not much will have changed for either team.

One thing that could hinder the 49ers is the absence of tight end George Kittle.  He has been ruled out of Sunday’s contest.  We all know just how much the Cardinals enjoy covering tight ends.

That doesn’t mean the Cardinals are off the hook, but they may have a little easier time without Kittle running free.  The 49ers will be without running back Matt Brieda as well but receiver Emmanuel Sanders is reportedly going to give it a go and play.

Still, the Cardinals are coming off a tough loss last Sunday to the Tampa Bay Buccaneers 30-27.  It was a game they should have won.

The 49ers are coming off a very tough loss to the Seattle Seahawks at home last Monday night in overtime 27-24.  It was their first loss of the season and also a game they were given multiple opportunities to win.

So both teams come in hungry to erase last week quickly and start fast this week.  That likely does not bode well for the Cardinals, despite the injuries to the 49ers.

The Cardinals will have David Johnson back on the field again.  He was benched after his fumble in the second half last week against the Bucs.  The Cardinals indicated that they would go running back by committee with him and Kenyan Drake for now.

There will be no Chase Edmonds again on Sunday.  He could be back the week after the bye, which falls next week for the Cardinals.

Defensive lineman Jonathan Bullard has been the only other Cardinal ruled out so far.  Linebacker Terrell Suggs is questionable as he missed practice both Thursday and Friday.