3 Best Bets for Arizona Cardinals vs. 49ers – Week 11

Oct 20, 2022; Glendale, Arizona, United States; Arizona Cardinals running back Keaontay Ingram (30) celebrates his touchdown run with teammate D.J. Humphries (74) against the New Orleans Saints at State Farm Stadium.Nfl Cardinals Saints Photos New Orleans Saints At Arizona Cardinals
Oct 20, 2022; Glendale, Arizona, United States; Arizona Cardinals running back Keaontay Ingram (30) celebrates his touchdown run with teammate D.J. Humphries (74) against the New Orleans Saints at State Farm Stadium.Nfl Cardinals Saints Photos New Orleans Saints At Arizona Cardinals /
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The Arizona Cardinals have been decimated with injuries, but with a potential Hopkins-Hollywood sighting, they still have hope. 

The Arizona Cardinals could inch closer to take the lead in the stagnant NFC West with a win over the San Francisco 49ers. And this one is projected to be a lower-scoring affair given the limited success each offense has seen over the first 10 weeks of the season.

But that doesn’t mean there aren’t a few good, and surprising bets, to make. Let’s check out the best bets for the Week 11 matchup.

1 – OVER 43.5 Over/Under

While neither the Arizona Cardinals nor the 49ers have great offenses this season, the Cardinals defense has been stagnant in the category while the offense may get a much-needed boost with Marquise Brown potentially returning to the fold.

Further, the 49ers are averaging 19.8 points per game and the Cardinals, 23.0, putting the two teams right in the neighborhood of the 43.5 mark. And given the potential dynamic duo at wideout, it could be enough of a curveball to the 49ers for the Cardinals to just encroach the 43.5 mark.

2 – First Half Winner – Arizona Cardinals

I’m going out on a limb here and saying the Cardinals make it two in a row in winning the first half. This projection banks on Hopkins and Brown starting simultaneously, with preferably Colt McCoy and his quick decision-making starting.

But the closer we get to Monday, the more that seems to be the case. Look for the Cardinals to square off with and move the ball methodically against yet another top-ranked defense in the NFL.

3 – Christian McCaffrey Scores

We’re turning to a TD scorer prop for this one, and there is no one likelier to find the end zone than Christian McCaffrey. So far with the 49ers, McCaffrey has three touchdowns, and four if you count a touchdown pass.

Overall, he is the queen on the NFL-size chessboard for this matchup. Expect McCaffrey to be a nightmare for the Cardinals, as he is for almost everybody he plays. Of the three best bets of the week, this one might be the safest.

Last Week’s Results…

Last week, I went an “incredible” 0 for 3, barely missing on each of my best bets for the Cardinals vs. Rams – I went with UNDER 40.5, knowing the Battle of the Backups could make this a low-scoring affair. I projected the first drive would end in a punt, but it ended in a field goal, and that the Rams would win the first quarter, but it instead resulted in a tie.

Related Story. Cardinals vs. 49ers Prediction and Odds – Week 11. light

This puts me at 15-15 on the season, so hopefully, a better outing this week will put me above 0.500 again for the season as we dive into the final seven weeks. We will find out in about 55 hours from now.

(Game odds refresh periodically and are subject to change)

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