Arizona Cardinals: 5 toughest games on schedule

By Scott Allen | May 10, 2020

SANTA CLARA, CALIFORNIA - NOVEMBER 17: Quarterback Kyler Murray #1 of the Arizona Cardinals scrambles with the football ahead of safety Jaquiski Tartt #29 of the San Francisco 49ers during the first half of the NFL game at Levi's Stadium on November 17, 2019 in Santa Clara, California. (Photo by Thearon W. Henderson/Getty Images) /

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ORCHARD PARK, NY – SEPTEMBER 25: Larry Fitzgerald #11 of the Arizona Cardinals runs with the ball during NFL game action as Corey Graham #20 of the Buffalo Bills tries to tackle him at New Era Field on September 25, 2016 in Orchard Park, New York. (Photo by Tom Szczerbowski/Getty Images) /

3. Buffalo Bills (week 10)

A changing of the guard in the AFC East is taking place. We don’t quite yet know how it will all play out but we’ve seen how the Bills have progressed over the last two years.

Quarterback Josh Allen and the Bills defense comes to town in November and what arguably could be the toughest home game of the season. A number of people making predictions have this game marked as a loss for the Cardinals.

It will be a great test for both sides of the ball for the Cardinals. Can their Air Raid offense penetrate a stellar Bills defense?

This game could also end up being a national game if the cards fall right. If not on Sunday Night Football, a national game on CBS, the network currently scheduled to air this game.

We will definitely know a lot more about both teams by the time this one rolls around. This will be the Bills first ride into Arizona since 2012.

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